Well i'm not a programmer, just a user of various software with many years of computer experience. Ive done quite a lot of testing of cudabiss and tested how to speed it up.
The main issues are that its in efficient made for old GTX 560 and below card. You can run nvprofiler on it and see all the weakness such as how poorly it uses the gpu memory etc.
Thats why on any modern gpu with cudabiss you need to maximise performance by running multiple instances at the same time.
Everyone here should be running version Cudabiss51264 as listed in my other post
from the original instructions
"Cudabiss22464 and Cudabiss44864 are intended for GTX460/465/470
Cudabiss24064 and Cudabiss48064 are intended for GTX480/570
Cudabiss25664 and Cudabiss51264 are intended for the GTX560"
just for reference The GTX 560 had just 336 cuda cores and 1 GB ram
A few tips
I tested Cudabiss in SLI mode using 2 gtx 980 at stock, no improvement whatsoever as expected, not supported even if gpu is forced to sli mode. Yes it will run but at no increased speeds. Much better to run 2 cards independently with multiple instances. (So don't waste time experiemnting with SLI there is no advantages to be gained)
Cudabiss itself uses very little CPU, around %7 cpu usage on my I7 5820k running 1 copy. It doesnt take advantage of multi threading. I have played around with pinning individual copys to specific cpu cores with higher priority. However theres little advantage to be gained unless your pc is running a lot of other tasks at the same time.
Memory bandwidth is important, to max out gpu performance, e.g going from 2133 MHZ ram to 3200 mhz ram will gain you performance. So enable XMP if you have it, also check out uncore mode in your bios (but thats another topic)
Gpu overclocking can gain you around %10 speed boost, Use msi afterburner, a basic guide below
don't touch any voltage options!
set power limits slider to maximum
set core clock anywhere between +150-250 mhz (this will entirely depend on your gpu and needs extensive testing)
leave memory clock alone (though this can add a small boost)
set gpu fan speed to %100 manual
For best performance of your GPU it should be installed using the NVCLEAN tool to remove all the nvidia bloatware
Also make sure you are runing your gpu in MSI mode
https://www.reddit.com/r/OptimizedGaming/comments/107blhi